Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice

A single-injection vaccine formulation that provides for both a prime and a boost immunization would have various advantages over a multiple-injection regime. For such a vaccine formulation, it is essential that the booster dose is released after a certain, preferably adjustable, lag time. In this s...

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Detalles Bibliográficos
Autores principales: Amssoms, Katie, Born, Philip A., Beugeling, Max, De Clerck, Ben, Van Gulck, Ellen, Hinrichs, Wouter L. J., Frijlink, Henderik W., Grasmeijer, Niels, Kraus, Guenter, Sutmuller, Roger, Simmen, Kenny, Baert, Lieven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117011/
https://www.ncbi.nlm.nih.gov/pubmed/30161264
http://dx.doi.org/10.1371/journal.pone.0202961

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