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Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data
Batch effects are technical sources of variation introduced by the necessity of conducting gene expression analyses on different dates due to the large number of biological samples in population-based studies. The aim of this study is to evaluate the performances of linear mixed models (LMM) and Com...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117018/ https://www.ncbi.nlm.nih.gov/pubmed/30161168 http://dx.doi.org/10.1371/journal.pone.0202947 |