Local release of tacrolimus from hydrogel-based drug delivery system is controlled by inflammatory enzymes in vivo and can be monitored non-invasively using in vivo imaging

BACKGROUND: Local drug delivery systems that adjust the release of immunosuppressive drug in response to the nature and intensity of inflammation represent a promising approach to reduce systemic immunosuppression and its side effects in allotransplantation. Here we aimed to demonstrate that release...

Descripción completa

Detalles Bibliográficos
Autores principales: Dzhonova, Dzhuliya, Olariu, Radu, Leckenby, Jonathan, Dhayani, Ashish, Vemula, Praveen Kumar, Prost, Jean-Christophe, Banz, Yara, Taddeo, Adriano, Rieben, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117083/
https://www.ncbi.nlm.nih.gov/pubmed/30161258
http://dx.doi.org/10.1371/journal.pone.0203409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117083/
https://www.ncbi.nlm.nih.gov/pubmed/30161258
http://dx.doi.org/10.1371/journal.pone.0203409

Ejemplares similares