A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein

The essential role of pathogens in host metabolism is widely recognized, yet the mechanisms by which they affect host physiology remain to be fully defined. Here, we found that NleB, an enteropathogenic Escherichia coli (EPEC) type III secretion system effector known to possess N-acetylglucosamine (...

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Detalles Bibliográficos
Autores principales: Xu, Chenxi, Liu, Xing, Zha, Huangyuan, Fan, Sijia, Zhang, Dawei, Li, Shan, Xiao, Wuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117090/
https://www.ncbi.nlm.nih.gov/pubmed/30125331
http://dx.doi.org/10.1371/journal.ppat.1007259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117090/
https://www.ncbi.nlm.nih.gov/pubmed/30125331
http://dx.doi.org/10.1371/journal.ppat.1007259

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