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A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein
The essential role of pathogens in host metabolism is widely recognized, yet the mechanisms by which they affect host physiology remain to be fully defined. Here, we found that NleB, an enteropathogenic Escherichia coli (EPEC) type III secretion system effector known to possess N-acetylglucosamine (...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117090/ https://www.ncbi.nlm.nih.gov/pubmed/30125331 http://dx.doi.org/10.1371/journal.ppat.1007259 |