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Short-term high glucose culture potentiates pancreatic beta cell function

The exposure of pancreatic islets to high glucose is believed to be one of the causal factors of the progressive lowering of insulin secretion in the development of type 2 diabetes. The progression of beta cell failure to type 2 diabetes is preceded by an early positive increase in the insulin secre...

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Detalles Bibliográficos
Autores principales: Rebelato, Eduardo, Santos, Laila R., Carpinelli, Angelo R., Rorsman, Patrik, Abdulkader, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117280/
https://www.ncbi.nlm.nih.gov/pubmed/30166558
http://dx.doi.org/10.1038/s41598-018-31325-5