Cargando…

DR region of Na(+)-K(+)-ATPase is a new target to protect heart against oxidative injury

Previous studies have shown that the activity and expression of Na(+)/K(+)-ATPase (NKA) are down-regulated in the failing hearts, and that an antibody against the DR-region of NKA (DR-Ab) can stimulate its activity. The present study was designed to investigate the beneficial effects of this antibod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hua, Fei, Wu, Zhiyuan, Yan, Xiaofei, Zheng, Jin, Sun, Haijian, Cao, Xu, Bian, Jin-Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117330/ https://www.ncbi.nlm.nih.gov/pubmed/30166619 http://dx.doi.org/10.1038/s41598-018-31460-z

Ejemplares similares

Na(+)/K(+)-ATPase-dependent autophagy protects brain against ischemic injury
por: Zhu, Mengyuan, et al.
Publicado: (2020)

DR-region of Na(+)/K(+) ATPase is a target to treat excitotoxicity and stroke
por: Shi, Meimei, et al.
Publicado: (2018)

Anti–Na(+)/K(+)-ATPase immunotherapy ameliorates α-synuclein pathology through activation of Na(+)/K(+)-ATPase α1–dependent autophagy
por: Cao, Lei, et al.
Publicado: (2021)

DR-region of Na(+)/K(+)-ATPase is a target to ameliorate hepatic insulin resistance in obese diabetic mice
por: Sun, Hai-Jian, et al.
Publicado: (2020)

DR region specific antibody ameliorated but ouabain worsened renal injury in nephrectomized rats through regulating Na,K-ATPase mediated signaling pathways
por: Wang, Juan, et al.
Publicado: (2019)

Na(+)/Ca(2+) exchange and Na(+)/K(+)-ATPase in the heart
por: Shattock, Michael J, et al.
Publicado: (2015)

Recent Advances in the Study of Na(+)/K(+)-ATPase in Neurodegenerative Diseases
por: Zhang, Xiaoyan, et al.
Publicado: (2022)

Na(+)/K(+)-ATPase DR region-specific antibody protects U251 cells against hypoxia reperfusion-induced injury via the PI3K/AKT and ERK pathways
por: Gong, Huilin, et al.
Publicado: (2017)

Stimulation of Na(+)/K(+)-ATPase with an Antibody against Its 4(th) Extracellular Region Attenuates Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy via an AMPK/SIRT3/PPARγ Signaling Pathway
por: Xiong, Siping, et al.
Publicado: (2019)

Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
por: Liu, Jiang, et al.
Publicado: (2017)

β subunit affects Na(+) and K(+) affinities of Na(+)/K(+)-ATPase: Na(+) and K(+) affinities of a hybrid Na(+)/K(+)-ATPase composed of insect α and mammalian β subunits
por: Homareda, Haruo, et al.
Publicado: (2022)

Hypoxic Stress-Dependent Regulation of Na,K-ATPase in Ischemic Heart Disease
por: Baloglu, Emel
Publicado: (2023)

C-peptide, Na(+),K(+)-ATPase, and Diabetes
por: Vague, P., et al.
Publicado: (2004)

Tuning of the Na,K-ATPase by the beta subunit
por: Hilbers, Florian, et al.
Publicado: (2016)

Transcriptional regulators of Na,K-ATPase subunits
por: Li, Zhiqin, et al.
Publicado: (2015)

Na(+), K(+)-ATPase Signaling and Bipolar Disorder
por: Lichtstein, David, et al.
Publicado: (2018)

Na/K-ATPase and Regulation of Sperm Function
por: Thundathil, Jacob C., et al.
Publicado: (2018)

The role of Na(+)‐K(+)‐ATPase in the epileptic brain
por: Sun, Jinyi, et al.
Publicado: (2022)

Oxidant effects on epithelial Na,K-ATPase gene expression and promoter function.
por: Wendt, C H, et al.
Publicado: (1998)

Oxidative Stress (Glutathionylation) and Na,K-ATPase Activity in Rat Skeletal Muscle
por: Juel, Carsten
Publicado: (2014)

RETRACTED ARTICLE: The Na/K-ATPase Oxidant Amplification Loop Regulates Aging
por: Sodhi, Komal, et al.
Publicado: (2018)

Retraction Note: The Na/K-ATPase oxidant amplification loop regulates aging
por: Sodhi, Komal, et al.
Publicado: (2022)

The parietal cell gastric H, K-ATPase also functions as the Na, K-ATPase and Ca-ATPase in altered states
por: Ray, Tushar
Publicado: (2013)

The Na(+),K(+)-ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state
por: Fruergaard, Marlene U., et al.
Publicado: (2022)

Ultrastructure of Na,K-transport vesicles reconstituted with purified renal Na,K-ATPase
Publicado: (1980)

Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy
por: Felippe Gonçalves-de-Albuquerque, Cassiano, et al.
Publicado: (2017)

Kinetics of Na-ATPase activity by the Na,K pump. Interactions of the phosphorylated intermediates with Na+, Tris+, and K+
Publicado: (1983)

Oxidant-Induced Alterations in the Adipocyte Transcriptome: Role of the Na,K-ATPase Oxidant Amplification Loop
por: Sodhi, Komal, et al.
Publicado: (2020)

Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy
por: Liu, Jiang, et al.
Publicado: (2016)

The Role of Na/K-ATPase Signaling in Oxidative Stress Related to Obesity and Cardiovascular Disease
por: Srikanthan, Krithika, et al.
Publicado: (2016)

Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration
por: Sodhi, Komal, et al.
Publicado: (2021)

Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration
por: Sodhi, Komal, et al.
Publicado: (2023)

Structural organization of (Na+ + K+)-ATPase in purified membranes
Publicado: (1984)

The modulation of erythrocyte Na(+)/K(+)-ATPase activity by curcumin
por: Singh, Prabhakar, et al.
Publicado: (2015)

Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase
por: Castillo, Juan P., et al.
Publicado: (2015)

“Oxygen Sensing” by Na,K-ATPase: These Miraculous Thiols
por: Bogdanova, Anna, et al.
Publicado: (2016)

Brain Na(+), K(+)-ATPase Activity In Aging and Disease
por: de Lores Arnaiz, Georgina Rodríguez, et al.
Publicado: (2014)

Specialized Functional Diversity and Interactions of the Na,K-ATPase
por: Matchkov, Vladimir V., et al.
Publicado: (2016)

Cellular Pathophysiology of Leptospirosis: Role of Na/K-ATPase
por: Gonçalves-de-Albuquerque, Cassiano Felippe, et al.
Publicado: (2023)

Na+ and K+ transport at basolateral membranes of epithelial cells. I. Stoichiometry of the Na,K-ATPase
Publicado: (1986)

Cannot write session to /tmp/vufind_sessions/sess_kshin3fa5fs7uvg4fjvplqghs7