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OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers

The pervasive role of microRNAs (miRNAs) in cancer pathobiology drives the introduction of new drug development approaches such as miRNA inhibition. In order to advance miRNA-therapeutics, meticulous screening strategies addressing specific tumor targets are needed. Small molecule inhibitors represe...

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Detalles Bibliográficos
Autores principales: Monroig-Bosque, Paloma del C., Shah, Maitri Y., Fu, Xiao, Fuentes-Mattei, Enrique, Ling, Hui, Ivan, Cristina, Nouraee, Nazila, Huang, Beibei, Chen, Lu, Pileczki, Valentina, Redis, Roxana S., Jung, Eun-Jung, Zhang, Xinna, Lehrer, Michael, Nagvekar, Rahul, Mafra, Ana Carolina P., Monroig-Bosque, Maria del Mar, Irimie, Alexandra, Rivera, Carlos, Dan Dumitru, Calin, Berindan-Neagoe, Ioana, Nikonowicz, Edward P., Zhang, Shuxing, Calin, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117344/
https://www.ncbi.nlm.nih.gov/pubmed/30166612
http://dx.doi.org/10.1038/s41598-018-30989-3