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The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism
Autistic spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social communication and restricted/repetitive behavior patterns or interests. Antagonists targeting histamine H3 receptor (H3R) are considered potential therapeutic agents for the therapeutic management...
Autores principales: | Eissa, Nermin, Jayaprakash, Petrilla, Azimullah, Sheikh, Ojha, Shreesh K., Al-Houqani, Mohammed, Jalal, Fakhreya Y., Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117350/ https://www.ncbi.nlm.nih.gov/pubmed/30166610 http://dx.doi.org/10.1038/s41598-018-31385-7 |
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