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In silico Description of LAT1 Transport Mechanism at an Atomistic Level
The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine...
Autores principales: | Palazzolo, Luca, Parravicini, Chiara, Laurenzi, Tommaso, Guerrini, Uliano, Indiveri, Cesare, Gianazza, Elisabetta, Eberini, Ivano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117385/ https://www.ncbi.nlm.nih.gov/pubmed/30197880 http://dx.doi.org/10.3389/fchem.2018.00350 |
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