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Low Peripheral T Follicular Helper Cells in Perinatally HIV-Infected Children Correlate With Advancing HIV Disease

BACKGROUND: T follicular helper (Tfh) cells are crucial for B cell differentiation and antigen-specific antibody production. Dysregulation of Tfh-mediated B cell help weakens B cell responses in HIV infection. Moreover, Tfh cells in the lymph node and peripheral blood comprise a significant portion...

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Detalles Bibliográficos
Autores principales: McCarty, Bret, Mwamzuka, Mussa, Marshed, Fatma, Generoso, Matthew, Alvarez, Patricia, Ilmet, Tiina, Kravietz, Adam, Ahmed, Aabid, Borkowsky, William, Unutmaz, Derya, Khaitan, Alka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117426/
https://www.ncbi.nlm.nih.gov/pubmed/30197641
http://dx.doi.org/10.3389/fimmu.2018.01901