Proliferation versus Differentiation: Redefining Retinoic Acid’s Role

Retinoic acid is commonly used in culture to differentiate stem cells into neurons and has established neural differentiation functions in vivo in developing and adult organisms. In this issue of Stem Cell Reports, Mishra et al. (2018) broaden its role in stem cell functions, showing that retinoic a...

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Detalles Bibliográficos
Autores principales: Mosher, Kira Irving, Schaffer, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117460/
https://www.ncbi.nlm.nih.gov/pubmed/29874625
http://dx.doi.org/10.1016/j.stemcr.2018.05.011
Descripción
Sumario:Retinoic acid is commonly used in culture to differentiate stem cells into neurons and has established neural differentiation functions in vivo in developing and adult organisms. In this issue of Stem Cell Reports, Mishra et al. (2018) broaden its role in stem cell functions, showing that retinoic acid is necessary for stem and progenitor cell proliferation in the adult brain.

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