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2i, or Not 2i: The Soliloquy of Nanog-Negative Mouse Embryonic Stem Cells
In this issue of Stem Cell Reports, Hastreiter et al. (2018) use continuous time-lapse imaging of mouse embryonic stem cells to investigate how the inhibition of GSK3b and MEK/ERK (2i) leads to homogeneous expression of the transcription factor Nanog. They show that both induction of Nanog expressio...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117476/ https://www.ncbi.nlm.nih.gov/pubmed/29996086 http://dx.doi.org/10.1016/j.stemcr.2018.06.017 |