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ICAM-1 Deficiency in the Bone Marrow Niche Impairs Quiescence and Repopulation of Hematopoietic Stem Cells

The bone marrow niche plays a critical role in controlling the fate of hematopoietic stem cells (HSCs) by integrating intrinsic and extrinsic signals. However, the molecular events in the HSC niche remain to be investigated. Here, we report that intercellular adhesion molecule-1 (ICAM-1) maintains H...

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Detalles Bibliográficos
Autores principales: Liu, Yu-feng, Zhang, Shao-ying, Chen, Ying-ying, Shi, Kun, Zou, Bin, Liu, Jun, Yang, Qiong, Jiang, Hua, Wei, Lai, Li, Chang-zheng, Zhao, Meng, Gabrilovich, Dmitry I., Zhang, Hui, Zhou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117479/
https://www.ncbi.nlm.nih.gov/pubmed/29937143
http://dx.doi.org/10.1016/j.stemcr.2018.05.016

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