Pravastatin alleviates lipopolysaccharide-induced placental TLR4 over-activation and promotes uterine arteriole remodeling without impairing rat fetal development

Preeclampsia is associated with over-activation of the innate immune system in the placenta, in which toll-like receptor 4 (TLR4) plays an essential part. With their potent anti-inflammatory effects, statins have been suggested as potential prevention or treatment of preeclampsia, although evidence...

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Detalles Bibliográficos
Autores principales: Yang, Muyi, Diao, Zhenyu, Wang, Zhiyin, Yan, Guijun, Zhao, Guangfeng, Zheng, Mingming, Dai, Anyi, Dai, Yimin, Hu, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117606/
https://www.ncbi.nlm.nih.gov/pubmed/30008464
http://dx.doi.org/10.7555/JBR.32.20180039

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