Cargando…

The Long Noncoding RNA MEG3 and its Target miR-147 Regulate JAK/STAT Pathway in Advanced Chronic Myeloid Leukemia

BACKGROUND: Long non-coding (lnc) RNAs plays an important role in chronic myeloid leukemia (CML). In this study, we aimed to uncover the mechanism of the lncRNA maternally expressed 3 (MEG3) and its target microRNA-147 (miR-147) in CML. METHODS: Sixty CML patients and 10 healthy donors were included...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zi-ye, Yang, Lin, Liu, Xiao-jun, Wang, Xing-zhe, Pan, Yu-xia, Luo, Jian-min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117736/ https://www.ncbi.nlm.nih.gov/pubmed/30072211 http://dx.doi.org/10.1016/j.ebiom.2018.07.013

Ejemplares similares

Corrigendum to “the long noncoding RNA MEG3 and its target miR-147 regulate JAK/STAT pathway in advanced chronic myeloid leukemia” [EBioMedicine 35 (2018) 61–75]
por: Li, Zi-ye, et al.
Publicado: (2018)

Restoring the Long Noncoding RNA MEG3 Indicates a Potential Role for JAK-STAT Signaling in Chronic Myeloid Leukemia
por: Olson, Thomas L., et al.
Publicado: (2018)

Long Noncoding RNA MEG3 Inhibits Cell Proliferation and Metastasis in Chronic Myeloid Leukemia via Targeting miR-184
por: Li, Jingdong, et al.
Publicado: (2018)

miR-155 meets the JAK/STAT pathway
por: Persson, Jenny Liao
Publicado: (2013)

Effect of MiR-210 on the Chemosensitivity of Breast Cancer by Regulating JAK-STAT Signaling Pathway
por: Xing, Zeyu, et al.
Publicado: (2021)

JAK-STAT in Early Hematopoiesis and Leukemia
por: Fasouli, Eirini Sofia, et al.
Publicado: (2021)

Clinical significance of miR-372 and miR-495 in acute myeloid leukemia
por: Zhang, Wei, et al.
Publicado: (2020)

Regulation of the miR-19b-mediated SOCS6-JAK2/STAT3 pathway by lncRNA MEG3 is involved in high glucose-induced apoptosis in hRMECs
por: Xiao, Fan, et al.
Publicado: (2020)

miR-19a: An Effective Regulator of SOCS3 and Enhancer of JAK-STAT Signalling
por: Collins, Aideen S., et al.
Publicado: (2013)

Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis
por: Li, Hong-Wei, et al.
Publicado: (2019)

MiR-375 mitigates retinal angiogenesis by depressing the JAK2/STAT3 pathway
por: Gong, Ruowen, et al.
Publicado: (2022)

The promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML)
por: Yan-Fang, Tao, et al.
Publicado: (2013)

Long noncoding RNA Meg3 sponges miR-708 to inhibit intestinal tumorigenesis via SOCS3-repressed cancer stem cells growth
por: Zhang, Shuo, et al.
Publicado: (2021)

“Seed-Milarity” Confers to hsa-miR-210 and hsa-miR-147b Similar Functional Activity
por: Bertero, Thomas, et al.
Publicado: (2012)

Ritanserin suppresses acute myeloid leukemia by inhibiting DGKα to downregulate phospholipase D and the Jak-Stat/MAPK pathway
por: Tan, Jinshui, et al.
Publicado: (2023)

Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion
por: Si, Xiaohui, et al.
Publicado: (2016)

Long noncoding RNA-MEG3 contributes to myocardial ischemia–reperfusion injury through suppression of miR-7-5p expression
por: Zou, Liyuan, et al.
Publicado: (2019)

Combining LSD1 and JAK-STAT inhibition targets Down syndrome-associated myeloid leukemia at its core
por: Grimm, Juliane, et al.
Publicado: (2022)

Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia
por: Fayyad-Kazan, Hussein, et al.
Publicado: (2013)

Circulating miR-92a, miR-143 and miR-342 in Plasma are Novel Potential Biomarkers for Acute Myeloid Leukemia
por: Elhamamsy, Amr Rafat, et al.
Publicado: (2017)

Long noncoding RNA ZFAS1 enhances adriamycin resistance in pediatric acute myeloid leukemia through the miR-195/Myb axis
por: Li, Qun, et al.
Publicado: (2019)

Prognostic value of miR-96 in patients with acute myeloid leukemia
por: Zhao, Jiangning, et al.
Publicado: (2014)

A tyrosine kinase-STAT5-miR21-PDCD4 regulatory axis in chronic and acute myeloid leukemia cells
por: Espadinha, Anne-Sophie, et al.
Publicado: (2017)

Long noncoding RNA MEG3 decreases the growth of head and neck squamous cell carcinoma by regulating the expression of miR‐421 and E‐cadherin
por: Ji, Yefeng, et al.
Publicado: (2020)

Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis
por: Li, Fenglin, et al.
Publicado: (2023)

Altered expression pattern of miR-29a, miR-29b and the target genes in myeloid leukemia
por: Xu, Ling, et al.
Publicado: (2014)

Icaritin Shows Potent Anti-Leukemia Activity on Chronic Myeloid Leukemia In Vitro and In Vivo by Regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT Signalings
por: Zhu, Jian feng, et al.
Publicado: (2011)

Osteoclast-Derived Exosomal miR-5134-5p Interferes with Alveolar Bone Homeostasis by Targeting the JAK2/STAT3 Axis
por: Pan, Lai, et al.
Publicado: (2023)

Long Noncoding RNA MEG3 Suppresses Glioma Cell Proliferation, Migration, and Invasion by Acting as a Competing Endogenous RNA of miR-19a
por: Qin, Nan, et al.
Publicado: (2017)

Overexpression of miR-210 is Associated with Poor Prognosis of Acute Myeloid Leukemia
por: Tang, Xiaoqiong, et al.
Publicado: (2015)

Global proteomics dataset of miR-126 overexpression in acute myeloid leukemia
por: Schoof, Erwin M., et al.
Publicado: (2016)

Clinical significance of dysregulation of miR-381 in pediatric acute myeloid leukemia
por: Zhang, Piqiang, et al.
Publicado: (2020)

miR-101 Represses T-Cell Acute Lymphoblastic Leukemia by Targeting CXCR7/STAT3 Axis
por: Yang, Xue-Yi, et al.
Publicado: (2019)

MiR-424 and miR-27a increase TRAIL sensitivity of acute myeloid leukemia by targeting PLAG1
por: Sun, Yan-ping, et al.
Publicado: (2016)

miR-140-5p induces cell apoptosis and decreases Warburg effect in chronic myeloid leukemia by targeting SIX1
por: Nie, Zi-Yuan, et al.
Publicado: (2019)

Analysis of the expression of D-dimer, CD147 and miR203 and their correlation in gastric cancer
por: Wu, Xiguo, et al.
Publicado: (2019)

Upregulation of miR-375 level ameliorates morphine analgesic tolerance in mouse dorsal root ganglia by inhibiting the JAK2/STAT3 pathway
por: Li, Haiqin, et al.
Publicado: (2017)

miR-342-3p Inhibits Acute Myeloid Leukemia Progression by Targeting SOX12
por: Wang, Ying, et al.
Publicado: (2022)

MiR-101 Protects Against the Cerebral I/R Injury Through Regulating JAK2/STAT3 Signaling Pathway
por: Guo, Xiaowang, et al.
Publicado: (2021)

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma
por: Sibbesen, Nina A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_aqd1kkat5t7skh01g1r4u42vte