Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1

BACKGROUND: Mitochondrial pyruvate import via mitochondrial pyruvate carrier (MPC) is a central step in hepatic gluconeogenesis. Berberine inhibits hepatic gluconeogenesis, but the mechanism is incompletely understood. This study aims to investigate whether berberine could reduce excessive hepatic g...

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Detalles Bibliográficos
Autores principales: Li, Aiyun, Liu, Qun, Li, Qiang, Liu, Baolin, Yang, Yang, Zhang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117739/
https://www.ncbi.nlm.nih.gov/pubmed/30093307
http://dx.doi.org/10.1016/j.ebiom.2018.07.039

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