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Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance

In OECD (Organization for Economic Co-operation and Development) countries, cancer is one of the main causes of death, lung cancer being one of the most aggressive. There are several techniques for the treatment of lung cancer, among which radiotherapy is one of the most effective and least invasive...

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Autores principales: Quiñones, Darío R., Soler-Egea, David, González-Pérez, Víctor, Reibke, Johanna, Simarro-Mondejar, Elena, Pérez-Feito, Ricardo, García-Manrique, Juan A., Crispín, Vicente, Moratal, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117797/
https://www.ncbi.nlm.nih.gov/pubmed/30061503
http://dx.doi.org/10.3390/ma11081317
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author Quiñones, Darío R.
Soler-Egea, David
González-Pérez, Víctor
Reibke, Johanna
Simarro-Mondejar, Elena
Pérez-Feito, Ricardo
García-Manrique, Juan A.
Crispín, Vicente
Moratal, David
author_facet Quiñones, Darío R.
Soler-Egea, David
González-Pérez, Víctor
Reibke, Johanna
Simarro-Mondejar, Elena
Pérez-Feito, Ricardo
García-Manrique, Juan A.
Crispín, Vicente
Moratal, David
author_sort Quiñones, Darío R.
collection PubMed
description In OECD (Organization for Economic Co-operation and Development) countries, cancer is one of the main causes of death, lung cancer being one of the most aggressive. There are several techniques for the treatment of lung cancer, among which radiotherapy is one of the most effective and least invasive for the patient. However, it has associated difficulties due to the moving target tumor. It is possible to reduce the side effects of radiotherapy by effectively tracking a tumor and reducing target irradiation margins. This paper presents a custom electromechanical system that follows the movement of a lung tumor. For this purpose, a hysteresis loop of human lung movement during breathing was studied to obtain its characteristic movement equation. The system is controlled by an Arduino, steppers motors and a customized 3D printed mechanism to follow the characteristic human breathing, obtaining an accurate trajectory. The developed device helps the verification of individualized radiation treatment plans and permits the improvement of radiotherapy quality assurance procedures.
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spelling pubmed-61177972018-09-05 Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance Quiñones, Darío R. Soler-Egea, David González-Pérez, Víctor Reibke, Johanna Simarro-Mondejar, Elena Pérez-Feito, Ricardo García-Manrique, Juan A. Crispín, Vicente Moratal, David Materials (Basel) Article In OECD (Organization for Economic Co-operation and Development) countries, cancer is one of the main causes of death, lung cancer being one of the most aggressive. There are several techniques for the treatment of lung cancer, among which radiotherapy is one of the most effective and least invasive for the patient. However, it has associated difficulties due to the moving target tumor. It is possible to reduce the side effects of radiotherapy by effectively tracking a tumor and reducing target irradiation margins. This paper presents a custom electromechanical system that follows the movement of a lung tumor. For this purpose, a hysteresis loop of human lung movement during breathing was studied to obtain its characteristic movement equation. The system is controlled by an Arduino, steppers motors and a customized 3D printed mechanism to follow the characteristic human breathing, obtaining an accurate trajectory. The developed device helps the verification of individualized radiation treatment plans and permits the improvement of radiotherapy quality assurance procedures. MDPI 2018-07-30 /pmc/articles/PMC6117797/ /pubmed/30061503 http://dx.doi.org/10.3390/ma11081317 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Quiñones, Darío R.
Soler-Egea, David
González-Pérez, Víctor
Reibke, Johanna
Simarro-Mondejar, Elena
Pérez-Feito, Ricardo
García-Manrique, Juan A.
Crispín, Vicente
Moratal, David
Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance
title Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance
title_full Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance
title_fullStr Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance
title_full_unstemmed Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance
title_short Open Source 3D Printed Lung Tumor Movement Simulator for Radiotherapy Quality Assurance
title_sort open source 3d printed lung tumor movement simulator for radiotherapy quality assurance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117797/
https://www.ncbi.nlm.nih.gov/pubmed/30061503
http://dx.doi.org/10.3390/ma11081317
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