Cargando…

Hepatitis viruses in Kathmandu, Nepal: hospital-based study

OBJECTIVE: The objective of this study was to see the aetiology and outcome of sporadic acute viral hepatitis (AVH) in Kathmandu, Nepal. RESULTS: Among 210 patients, 94 (45%) were male and 116 (55%) were female. Mean age was 30 years. 52 (24.7%) out of 210 were positive for either of the hepatitis v...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, Birendra Prasad, Adhikari, Anurag, Chaudhary, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117890/
https://www.ncbi.nlm.nih.gov/pubmed/30165899
http://dx.doi.org/10.1186/s13104-018-3739-1
_version_ 1783351831602135040
author Gupta, Birendra Prasad
Adhikari, Anurag
Chaudhary, Santosh
author_facet Gupta, Birendra Prasad
Adhikari, Anurag
Chaudhary, Santosh
author_sort Gupta, Birendra Prasad
collection PubMed
description OBJECTIVE: The objective of this study was to see the aetiology and outcome of sporadic acute viral hepatitis (AVH) in Kathmandu, Nepal. RESULTS: Among 210 patients, 94 (45%) were male and 116 (55%) were female. Mean age was 30 years. 52 (24.7%) out of 210 were positive for either of the hepatitis virus infection. Major causative agent for AVH among hepatitis positive patients were hepatitis E virus (HEV) in 36 (69.2%), followed by hepatitis A virus (HAV) 8 (15.3%), hepatitis B virus (HBV) 7 (13.4%) and hepatitis C virus (HCV) 1 (1.9%). The 158 (75.3%) patient were negative for all hepatitis viral markers. Co-infections with more than one virus were found in 4 (7.6%) patients. All liver-specific enzymes including bilirubin increased in hepatitis-infected patients. We found large number circulation of HEV in Kathmandu, Nepal, indicating that this region is endemic for hepatitis virus infection.
format Online
Article
Text
id pubmed-6117890
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-61178902018-09-05 Hepatitis viruses in Kathmandu, Nepal: hospital-based study Gupta, Birendra Prasad Adhikari, Anurag Chaudhary, Santosh BMC Res Notes Research Note OBJECTIVE: The objective of this study was to see the aetiology and outcome of sporadic acute viral hepatitis (AVH) in Kathmandu, Nepal. RESULTS: Among 210 patients, 94 (45%) were male and 116 (55%) were female. Mean age was 30 years. 52 (24.7%) out of 210 were positive for either of the hepatitis virus infection. Major causative agent for AVH among hepatitis positive patients were hepatitis E virus (HEV) in 36 (69.2%), followed by hepatitis A virus (HAV) 8 (15.3%), hepatitis B virus (HBV) 7 (13.4%) and hepatitis C virus (HCV) 1 (1.9%). The 158 (75.3%) patient were negative for all hepatitis viral markers. Co-infections with more than one virus were found in 4 (7.6%) patients. All liver-specific enzymes including bilirubin increased in hepatitis-infected patients. We found large number circulation of HEV in Kathmandu, Nepal, indicating that this region is endemic for hepatitis virus infection. BioMed Central 2018-08-30 /pmc/articles/PMC6117890/ /pubmed/30165899 http://dx.doi.org/10.1186/s13104-018-3739-1 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Gupta, Birendra Prasad
Adhikari, Anurag
Chaudhary, Santosh
Hepatitis viruses in Kathmandu, Nepal: hospital-based study
title Hepatitis viruses in Kathmandu, Nepal: hospital-based study
title_full Hepatitis viruses in Kathmandu, Nepal: hospital-based study
title_fullStr Hepatitis viruses in Kathmandu, Nepal: hospital-based study
title_full_unstemmed Hepatitis viruses in Kathmandu, Nepal: hospital-based study
title_short Hepatitis viruses in Kathmandu, Nepal: hospital-based study
title_sort hepatitis viruses in kathmandu, nepal: hospital-based study
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117890/
https://www.ncbi.nlm.nih.gov/pubmed/30165899
http://dx.doi.org/10.1186/s13104-018-3739-1
work_keys_str_mv AT guptabirendraprasad hepatitisvirusesinkathmandunepalhospitalbasedstudy
AT adhikarianurag hepatitisvirusesinkathmandunepalhospitalbasedstudy
AT chaudharysantosh hepatitisvirusesinkathmandunepalhospitalbasedstudy