Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)

Mutation acquisition is a major mechanism of bacterial antibiotic resistance that remains insufficiently characterised. Here we present RM-seq, a new amplicon-based deep sequencing workflow based on a molecular barcoding technique adapted from Low Error Amplicon sequencing (LEA-seq). RM-seq allows d...

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Detalles Bibliográficos
Autores principales: Guérillot, Romain, Li, Lucy, Baines, Sarah, Howden, Brian, Schultz, Mark B., Seemann, Torsten, Monk, Ian, Pidot, Sacha J., Gao, Wei, Giulieri, Stefano, Gonçalves da Silva, Anders, D’Agata, Anthony, Tomita, Takehiro, Peleg, Anton Y., Stinear, Timothy P., Howden, Benjamin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117896/
https://www.ncbi.nlm.nih.gov/pubmed/30165908
http://dx.doi.org/10.1186/s13073-018-0572-z

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