Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome

BACKGROUND: Down syndrome (DS) is a common developmental disorder resulting from the presence of an additional copy of chromosome 21. Abnormalities in dopamine signaling are suggested to be involved in cognitive dysfunction, one of the symptoms of DS, but the pathophysiological mechanism has not bee...

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Detalles Bibliográficos
Autores principales: Pham, Thanh Thi Mai, Kato, Hiroki, Yamaza, Haruyoshi, Masuda, Keiji, Hirofuji, Yuta, Sato, Hiroshi, Nguyen, Huong Thi Nguyen, Han, Xu, Zhang, Yu, Taguchi, Tomoaki, Nonaka, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117917/
https://www.ncbi.nlm.nih.gov/pubmed/30170556
http://dx.doi.org/10.1186/s12883-018-1140-2

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