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Chitinase 3-like 1-CD44 interaction promotes metastasis and epithelial-to-mesenchymal transition through β-catenin/Erk/Akt signaling in gastric cancer

BACKGROUND: Enzymatically inactive chitinase-like protein CHI3L1 drives inflammatory response and promotes tumor progression. However, its role in gastric cancer (GC) tumorigenesis and metastasis has not yet been fully elucidated. We determined the significance of CHI3L1 expression in patients with...

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Detalles Bibliográficos
Autores principales: Geng, Biao, Pan, Jinshun, Zhao, Ting, Ji, Jie, Zhang, Chen, Che, Ying, Yang, Jing, Shi, Hui, Li, Juan, Zhou, Hong, Mu, Xianmin, Xu, Che, Wang, Chao, Xu, Yue, Liu, Zheng, Wen, Hao, You, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117920/
https://www.ncbi.nlm.nih.gov/pubmed/30165890
http://dx.doi.org/10.1186/s13046-018-0876-2

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