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Targeting the Notch1 oncogene by miR-139-5p inhibits glioma metastasis and epithelial-mesenchymal transition (EMT)

BACKGROUND: Glioma metastasis, invasion, epithelial-mesenchymal transition (EMT) and chemoresistance indicate poor prognosis. Accumulating evidence reveals that Notch1 is an important factor in tumour progression. However, the role of Notch1 in glioma EMT and associated microRNAs (miRNAs) with the N...

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Detalles Bibliográficos
Autores principales:	Li, Jianlong, Li, Qingbin, Lin, Lin, Wang, Rui, Chen, Lingchao, Du, Wenzhong, Jiang, Chuanlu, Li, Ruiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117922/ https://www.ncbi.nlm.nih.gov/pubmed/30170559 http://dx.doi.org/10.1186/s12883-018-1139-8

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