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A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism

Trypanosomatid parasites are the infectious agents causing Chagas disease, visceral and cutaneous leishmaniasis and human African trypanosomiasis. Recent work of others has implicated an aldo-keto reductase (AKR) in the susceptibility and resistance of Trypanosoma cruzi to benznidazole, a drug used...

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Detalles Bibliográficos
Autores principales: Roberts, Adam J., Dunne, Joanne, Scullion, Paul, Norval, Suzanne, Fairlamb, Alan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117947/
https://www.ncbi.nlm.nih.gov/pubmed/30045874
http://dx.doi.org/10.1042/BCJ20180232

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