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A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism
Trypanosomatid parasites are the infectious agents causing Chagas disease, visceral and cutaneous leishmaniasis and human African trypanosomiasis. Recent work of others has implicated an aldo-keto reductase (AKR) in the susceptibility and resistance of Trypanosoma cruzi to benznidazole, a drug used...
Autores principales: | Roberts, Adam J., Dunne, Joanne, Scullion, Paul, Norval, Suzanne, Fairlamb, Alan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117947/ https://www.ncbi.nlm.nih.gov/pubmed/30045874 http://dx.doi.org/10.1042/BCJ20180232 |
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