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BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer

BACKGROUND: Angiogenesis has become an attractive target for cancer therapy. However, despite the initial success of anti-VEGF (Vascular endothelial growth factor) therapies, the overall survival appears only modestly improved and resistance to therapy often develops. Other anti-angiogenic targets a...

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Detalles Bibliográficos
Autores principales: Ouarné, Marie, Bouvard, Claire, Boneva, Gabriela, Mallet, Christine, Ribeiro, Johnny, Desroches-Castan, Agnès, Soleilhac, Emmanuelle, Tillet, Emmanuelle, Peyruchaud, Olivier, Bailly, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118004/
https://www.ncbi.nlm.nih.gov/pubmed/30165893
http://dx.doi.org/10.1186/s13046-018-0885-1