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Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium
Protein kinase C (PKC) isozymes are commonly recognized as oncoproteins based on their activation by tumor-promoting phorbol esters. However, accumulating evidence indicates that PKCs can be inhibitory in some cancers, with recent findings propelling a shift in focus to understanding tumor suppressi...
Autores principales: | Hsu, Alice H., Lum, Michelle A., Shim, Kang-Sup, Frederick, Peter J., Morrison, Carl D., Chen, Baojiang, Lele, Subodh M., Sheinin, Yuri M., Daikoku, Takiko, Dey, Sudhansu K., Leone, Gustavo, Black, Adrian R., Black, Jennifer D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118133/ https://www.ncbi.nlm.nih.gov/pubmed/30021163 http://dx.doi.org/10.1016/j.celrep.2018.06.067 |
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