siRNA Knockdown of RRM2 Effectively Suppressed Pancreatic Tumor Growth Alone or Synergistically with Doxorubicin

Pancreatic cancer is currently one of the deadliest of the solid malignancies, whose incidence and death rates are increasing consistently during the past 30 years. Ribonucleotide reductase (RR) is a rate-limiting enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides, whic...

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Detalles Bibliográficos
Autores principales: Zheng, Shuquan, Wang, Xiaoxia, Weng, Yu-Hua, Jin, Xingyu, Ji, Jia-Li, Guo, Liangxia, Hu, Bo, Liu, Nan, Cheng, Qiang, Zhang, Jianqi, Bai, Huicheng, Yang, Tongren, Xia, Xin-Hua, Zhang, Hong-Yan, Gao, Shan, Huang, Yuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118156/
https://www.ncbi.nlm.nih.gov/pubmed/30153565
http://dx.doi.org/10.1016/j.omtn.2018.08.003

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