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Spectroscopic and molecular modeling studies of binding interaction between bovine serum albumin and roflumilast

BACKGROUND: The binding interaction between bovine serum albumin (BSA) and roflumilast (ROF) was explored in this study. The binding of drugs to albumin plays a vital role in their pharmacokinetics and pharmacodynamics in vivo. The mechanisms involved in the interaction between BSA and ROF was studi...

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Detalles Bibliográficos
Autores principales:	Wani, Tanveer A, Bakheit, Ahmed H, Ansari, Mohammed Nazam, Al-Majed, Abdul-Rahman A, Al-Qahtani, Bakr M, Zargar, Seema
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118266/ https://www.ncbi.nlm.nih.gov/pubmed/30214151 http://dx.doi.org/10.2147/DDDT.S169697

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