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c-Myb regulates transcriptional activation of miR-143/145 in vascular smooth muscle cells

BACKGROUND: MicroRNAs (miR) are small non-coding RNAs that regulate diverse biological functions. The bicistronic gene miR-143/145 determines cell fate and phenotype of vascular smooth muscle cells (VSMC), in part, by destabilizing Elk-1 mRNA. The transcription factor c-Myb also regulates differenti...

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Detalles Bibliográficos
Autores principales: Chandy, Mark, Ishida, Masayoshi, Shikatani, Eric A., El-Mounayri, Omar, Park, Lawrence Changsu, Afroze, Talat, Wang, Tao, Marsden, Philip A., Husain, Mansoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118359/
https://www.ncbi.nlm.nih.gov/pubmed/30169548
http://dx.doi.org/10.1371/journal.pone.0202778

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