Cargando…
c-Myb regulates transcriptional activation of miR-143/145 in vascular smooth muscle cells
BACKGROUND: MicroRNAs (miR) are small non-coding RNAs that regulate diverse biological functions. The bicistronic gene miR-143/145 determines cell fate and phenotype of vascular smooth muscle cells (VSMC), in part, by destabilizing Elk-1 mRNA. The transcription factor c-Myb also regulates differenti...
Autores principales: | Chandy, Mark, Ishida, Masayoshi, Shikatani, Eric A., El-Mounayri, Omar, Park, Lawrence Changsu, Afroze, Talat, Wang, Tao, Marsden, Philip A., Husain, Mansoor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118359/ https://www.ncbi.nlm.nih.gov/pubmed/30169548 http://dx.doi.org/10.1371/journal.pone.0202778 |
Ejemplares similares
-
miR-145 and miR-143 Regulate Smooth Muscle Cell Fate Decisions
por: Cordes, Kimberly R., et al.
Publicado: (2009) -
The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease
por: Elia, Leonardo, et al.
Publicado: (2009) -
The function of miR-143, miR-145 and the MiR-143 host gene in cardiovascular development and disease
por: Vacante, Francesca, et al.
Publicado: (2019) -
Flank Sequences of miR‐145/143 and Their Aberrant Expression in Vascular Disease: Mechanism and Therapeutic Application
por: Liu, Xiaojun, et al.
Publicado: (2013) -
TWIST1 induces phenotypic switching of vascular smooth muscle cells by downregulating p68 and microRNA‐143/145
por: Zhang, Jing, et al.
Publicado: (2021)