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VapC proteins from Mycobacterium tuberculosis share ribonuclease sequence specificity but differ in regulation and toxicity

The chromosome of Mycobacterium tuberculosis (Mtb) contains a large number of Type II toxin-antitoxin (TA) systems. The majority of these belong to the VapBC TA family, characterised by the VapC protein consisting of a PIN domain with four conserved acidic residues, and proposed ribonuclease activit...

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Detalles Bibliográficos
Autores principales:	Sharrock, Abigail, Ruthe, Alaine, Andrews, Emma S. V., Arcus, Vickery A., Hicks, Joanna L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118392/ https://www.ncbi.nlm.nih.gov/pubmed/30169502 http://dx.doi.org/10.1371/journal.pone.0203412

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