Control of Listeria monocytogenes infection requires classical IL-6 signaling in myeloid cells

IL-6 is required for the response of mice against Listeria monocytogenes. Control of infection depends on classical IL-6 signaling via membrane IL-6Rα, but IL-6 target cells and protective mechanisms remain unclear. We used mice with IL-6Rα-deficiency in T cells (Il6ra(fl/fl)×CD4(cre)) or myeloid ce...

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Detalles Bibliográficos
Autores principales: Lücke, Karsten, Yan, Isabell, Krohn, Sonja, Volmari, Annika, Klinge, Stefanie, Schmid, Joanna, Schumacher, Valéa, Steinmetz, Oliver M., Rose-John, Stefan, Mittrücker, Hans-Willi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118394/
https://www.ncbi.nlm.nih.gov/pubmed/30169526
http://dx.doi.org/10.1371/journal.pone.0203395

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