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E-cadherin in Contact Inhibition and Cancer

E-cadherin is a key component of the adherens junctions that are integral in cell adhesion and maintaining epithelial phenotype of cells. Homophilic E-cadherin binding between cells is important in mediating contact inhibition of proliferation when cells reach confluence. Loss of E-cadherin expressi...

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Detalles Bibliográficos
Autores principales: Mendonsa, Alisha, Na, Tae-Young, Gumbiner, Barry M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119098/
https://www.ncbi.nlm.nih.gov/pubmed/29780167
http://dx.doi.org/10.1038/s41388-018-0304-2