Cargando…
NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis
In addition to their hemostatic function, platelets play an important role in regulating the inflammatory response. The platelet NLRP3 inflammasome not only promotes interleukin-1β secretion, but was also found to be upregulated during platelet activation and thrombus formation in vitro. However, th...
Autores principales: | Qiao, Jianlin, Wu, Xiaoqing, Luo, Qi, Wei, Guangyu, Xu, Mengdi, Wu, Yulu, Liu, Yun, Li, Xiaoqian, Zi, Jie, Ju, Wen, Fu, Lin, Chen, Chong, Wu, Qingyun, Zhu, Shengyun, Qi, Kunming, Li, Depeng, Li, Zhenyu, Andrews, Robert K., Zeng, Lingyu, Gardiner, Elizabeth E., Xu, Kailin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119128/ https://www.ncbi.nlm.nih.gov/pubmed/29794149 http://dx.doi.org/10.3324/haematol.2018.191700 |
Ejemplares similares
-
An absence of platelet activation following thalidomide treatment in vitro or in vivo
por: Qiao, Jianlin, et al.
Publicado: (2017) -
Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors
por: Luo, Qi, et al.
Publicado: (2018) -
Migfilin supports hemostasis and thrombosis through regulating platelet aIIbβ3 outside-in signaling
por: Zhou, Yangfan, et al.
Publicado: (2019) -
Macrophages ameliorate bone marrow inflammatory injury and promote hematopoiesis in mice following hematopoietic stem cell transplantation
por: Qiao, Jianlin, et al.
Publicado: (2018) -
Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation
por: Qiao, Jianlin, et al.
Publicado: (2015)