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Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

Severe thrombocytopenia (≤50×10(9) platelets/L) due to hematological malignancy and intensive chemotherapy is associated with an increased risk of clinically significant bleeding. Since the bleeding risk is not linked to the platelet count only, other hemostatic factors must be involved. We studied...

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Detalles Bibliográficos
Autores principales: Baaten, Constance C. F. M. J., Moenen, Floor C. J. I., Henskens, Yvonne M. C., Swieringa, Frauke, Wetzels, Rick J. H., van Oerle, René, Heijnen, Harry F. G., ten Cate, Hugo, Holloway, Graham P., Beckers, Erik A. M., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119160/
https://www.ncbi.nlm.nih.gov/pubmed/29880611
http://dx.doi.org/10.3324/haematol.2017.185165