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Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort

In this study, we aimed to test if the schizophrenia (SCZ) polygenic risk score (PRS) was associated with clinical symptoms in (a) the first episode of psychosis pre-treatment (FEP), (b) at nine weeks after initiation of risperidone treatment (FEP-9W) and (c) with the response to risperidone. We per...

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Detalles Bibliográficos
Autores principales:	Santoro, Marcos Leite, Ota, Vanessa, de Jong, Simone, Noto, Cristiano, Spindola, Leticia M., Talarico, Fernanda, Gouvea, Eduardo, Lee, Sang Hyuck, Moretti, Patricia, Curtis, Charles, Patel, Hamel, Newhouse, Stephen, Carvalho, Carolina Muniz, Gadelha, Ary, Cordeiro, Quirino, Bressan, Rodrigo Affonseca, Belangero, Sintia Iole, Breen, Gerome
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119191/ https://www.ncbi.nlm.nih.gov/pubmed/30171181 http://dx.doi.org/10.1038/s41398-018-0230-7

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