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A loop-mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy
BACKGROUND: JC polyomavirus (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunosuppressed patients. PML usually has a poor prognosis. Detection and quantification of the JCV genome in cerebrospinal fluid (C...
Autores principales: | Kinoshita, Hitomi, Nakamichi, Kazuo, Lim, Chang-Kweng, Takayama-Ito, Mutsuyo, Wang, Lixin, Iizuka, Itoe, Kurane, Ichiro, Saijo, Masayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119251/ https://www.ncbi.nlm.nih.gov/pubmed/30170628 http://dx.doi.org/10.1186/s12985-018-1046-z |
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