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XRCC2 mutation causes meiotic arrest, azoospermia and infertility
BACKGROUND: Meiotic homologous recombination (HR) plays an essential role in gametogenesis. In most eukaryotes, meiotic HR is mediated by two recombinase systems: ubiquitous RAD51 and meiosis-specific DMC1. In the RAD51-mediated HR system, RAD51 and five RAD51 paralogues are essential for normal RAD...
Autores principales: | Yang, Yongjia, Guo, Jihong, Dai, Lei, Zhu, Yimin, Hu, Hao, Tan, Lihong, Chen, Weijian, Liang, Desheng, He, Jingliang, Tu, Ming, Wang, Kewei, Wu, Lingqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119352/ https://www.ncbi.nlm.nih.gov/pubmed/30042186 http://dx.doi.org/10.1136/jmedgenet-2017-105145 |
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