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Prevalence and clinicopathological characteristics of mismatch repair-deficient colorectal carcinoma in early onset cases as compared with late-onset cases: a retrospective cross-sectional study in Northeastern Iran

OBJECTIVES: Lynch syndrome (LS), a genetically inherited autosomal disorder, increases the incidence of colorectal carcinoma (CRC). We aimed to perform a universal strategy to assess the prevalence and clinicopathological characteristics of early onset CRCs at high risk of LS versus late-onset ones...

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Detalles Bibliográficos
Autores principales: Goshayeshi, Ladan, Ghaffarzadegan, Kamran, Khooei, Alireza, Esmaeilzadeh, Abbas, Rahmani Khorram, Mahla, Mosannen Mozaffari, Hooman, Kiani, Behzad, Hoseini, Benyamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119423/
https://www.ncbi.nlm.nih.gov/pubmed/30166308
http://dx.doi.org/10.1136/bmjopen-2018-023102