Cargando…

Primary pulmonary malignant melanoma: Case report and literature review

Primary malignant melanoma of the lung is an extremely rare pulmonary carcinoma. Only 45 cases have been reported in the literature. Herein, we report a case of a 46‐year‐old male patient with an O Rh negative blood type who presented with pulmonary bronchial symptoms and underwent lobectomy. Geneti...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Yuequan, Bing, Zhongxing, Xu, Xiaohui, Cui, Yushang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119615/
https://www.ncbi.nlm.nih.gov/pubmed/30062692
http://dx.doi.org/10.1111/1759-7714.12798
_version_ 1783352106404544512
author Shi, Yuequan
Bing, Zhongxing
Xu, Xiaohui
Cui, Yushang
author_facet Shi, Yuequan
Bing, Zhongxing
Xu, Xiaohui
Cui, Yushang
author_sort Shi, Yuequan
collection PubMed
description Primary malignant melanoma of the lung is an extremely rare pulmonary carcinoma. Only 45 cases have been reported in the literature. Herein, we report a case of a 46‐year‐old male patient with an O Rh negative blood type who presented with pulmonary bronchial symptoms and underwent lobectomy. Genetic testing was also performed but no targetable mutations were found, and the patient's PD‐L1 RNA level was low. He developed brain metastasis four months after surgery and received radiotherapy but died 21 months after diagnosis. We review the published cases of this rare pulmonary lesion.
format Online
Article
Text
id pubmed-6119615
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley & Sons Australia, Ltd
record_format MEDLINE/PubMed
spelling pubmed-61196152018-09-05 Primary pulmonary malignant melanoma: Case report and literature review Shi, Yuequan Bing, Zhongxing Xu, Xiaohui Cui, Yushang Thorac Cancer Case Reports Primary malignant melanoma of the lung is an extremely rare pulmonary carcinoma. Only 45 cases have been reported in the literature. Herein, we report a case of a 46‐year‐old male patient with an O Rh negative blood type who presented with pulmonary bronchial symptoms and underwent lobectomy. Genetic testing was also performed but no targetable mutations were found, and the patient's PD‐L1 RNA level was low. He developed brain metastasis four months after surgery and received radiotherapy but died 21 months after diagnosis. We review the published cases of this rare pulmonary lesion. John Wiley & Sons Australia, Ltd 2018-07-30 2018-09 /pmc/articles/PMC6119615/ /pubmed/30062692 http://dx.doi.org/10.1111/1759-7714.12798 Text en © 2018 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Shi, Yuequan
Bing, Zhongxing
Xu, Xiaohui
Cui, Yushang
Primary pulmonary malignant melanoma: Case report and literature review
title Primary pulmonary malignant melanoma: Case report and literature review
title_full Primary pulmonary malignant melanoma: Case report and literature review
title_fullStr Primary pulmonary malignant melanoma: Case report and literature review
title_full_unstemmed Primary pulmonary malignant melanoma: Case report and literature review
title_short Primary pulmonary malignant melanoma: Case report and literature review
title_sort primary pulmonary malignant melanoma: case report and literature review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119615/
https://www.ncbi.nlm.nih.gov/pubmed/30062692
http://dx.doi.org/10.1111/1759-7714.12798
work_keys_str_mv AT shiyuequan primarypulmonarymalignantmelanomacasereportandliteraturereview
AT bingzhongxing primarypulmonarymalignantmelanomacasereportandliteraturereview
AT xuxiaohui primarypulmonarymalignantmelanomacasereportandliteraturereview
AT cuiyushang primarypulmonarymalignantmelanomacasereportandliteraturereview