A 1 week IGF‐1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep

Fetal insulin is critical for regulation of growth. Insulin concentrations are partly determined by the amount of β‐cells present and their insulin content. Insulin‐like growth factor‐1 (IGF‐1) is a fetal anabolic growth factor which also impacts β‐cell mass in models of β‐cell injury and diabetes....

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Detalles Bibliográficos
Autores principales: White, Alicia, Louey, Samantha, Chang, Eileen I, Boehmer, Brit H., Goldstrohm, David, Jonker, Sonnet S., Rozance, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119661/
https://www.ncbi.nlm.nih.gov/pubmed/30175552
http://dx.doi.org/10.14814/phy2.13840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119661/
https://www.ncbi.nlm.nih.gov/pubmed/30175552
http://dx.doi.org/10.14814/phy2.13840

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