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A 1 week IGF‐1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep
Fetal insulin is critical for regulation of growth. Insulin concentrations are partly determined by the amount of β‐cells present and their insulin content. Insulin‐like growth factor‐1 (IGF‐1) is a fetal anabolic growth factor which also impacts β‐cell mass in models of β‐cell injury and diabetes....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119661/ https://www.ncbi.nlm.nih.gov/pubmed/30175552 http://dx.doi.org/10.14814/phy2.13840 |