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Discontinuation of carbamazepine due to concerns of long‐term consequences of enzyme induction

OBJECTIVE: Treatment with carbamazepine (CBZ), a potent enzyme inducer, is known to affect the lipid profile, steroid, and vitamin D metabolism. Consequently, it has been postulated that patients on CBZ should be switched to noninducing antiepileptic drugs (AEDs). However, little is known about the...

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Detalles Bibliográficos
Autores principales: Mäkinen, Jussi, Rainesalo, Sirpa, Raitanen, Jani, Saarinen, Jukka, Sandell, Satu, Peltola, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119761/
https://www.ncbi.nlm.nih.gov/pubmed/30187004
http://dx.doi.org/10.1002/epi4.12227