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A Five-Component Biginelli-Diels-Alder Cascade Reaction
A new multi-component condensation was discovered during the reaction of a urea, β-keto ester, and formaldehyde. In the presence of catalytic indium bromide, a Biginelli dihydropyrimidinone intermediate was further converted to a five-component condensation product through a formal hetero Diels-Alde...
Autores principales: | Maskrey, Taber S., Frischling, Madeline C., Rice, Mikhaila L., Wipf, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119773/ https://www.ncbi.nlm.nih.gov/pubmed/30211156 http://dx.doi.org/10.3389/fchem.2018.00376 |
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