Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants

The genetic architecture of late-onset Alzheimer disease (AD) in African Americans (AAs) differs from that in persons of European ancestry. In addition to APOE, genome-wide association studies (GWASs) of AD in AA samples have implicated ABCA7, COBL, and SLC10A2 as AA-AD risk genes. Previously, we id...

Descripción completa

Detalles Bibliográficos
Autores principales: Logue, Mark W., Lancour, Daniel, Farrell, John, Simkina, Irina, Fallin, M. Daniele, Lunetta, Kathryn L., Farrer, Lindsay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119822/
https://www.ncbi.nlm.nih.gov/pubmed/30210277
http://dx.doi.org/10.3389/fnins.2018.00592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119822/
https://www.ncbi.nlm.nih.gov/pubmed/30210277
http://dx.doi.org/10.3389/fnins.2018.00592

Ejemplares similares