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Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants

The genetic architecture of late-onset Alzheimer disease (AD) in African Americans (AAs) differs from that in persons of European ancestry. In addition to APOE, genome-wide association studies (GWASs) of AD in AA samples have implicated ABCA7, COBL, and SLC10A2 as AA-AD risk genes. Previously, we id...

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Detalles Bibliográficos
Autores principales:	Logue, Mark W., Lancour, Daniel, Farrell, John, Simkina, Irina, Fallin, M. Daniele, Lunetta, Kathryn L., Farrer, Lindsay A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119822/ https://www.ncbi.nlm.nih.gov/pubmed/30210277 http://dx.doi.org/10.3389/fnins.2018.00592

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