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Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis
Discovered in 1991 in a screen for genes involved in spindle pole body duplication, the monopolar spindle 1 (Mps1) kinase has since claimed a central role in processes that ensure error-free chromosome segregation. As a result, Mps1 kinase activity has become an attractive candidate for pharmaceutic...
Autores principales: | Pachis, Spyridon T., Kops, Geert J. P. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119859/ https://www.ncbi.nlm.nih.gov/pubmed/30111590 http://dx.doi.org/10.1098/rsob.180109 |
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