Cargando…
Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer
Academic translational research is growing at a great pace at a time in which questions have been raised about the reproducibility of preclinical findings. The development of Hedgehog (HH) pathway inhibitors for the treatment of cancer over the past two decades offers a case study for understanding...
Autor principal: | Curran, Tom |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119869/ https://www.ncbi.nlm.nih.gov/pubmed/30068568 http://dx.doi.org/10.1098/rsob.180098 |
Ejemplares similares
-
Drugging Hedgehog: signaling the pathway to translation
por: Carney, Tom J, et al.
Publicado: (2013) -
The Economics of Reproducibility in Preclinical Research
por: Freedman, Leonard P., et al.
Publicado: (2015) -
Methodological Rigor in Preclinical Cardiovascular Studies: Targets to Enhance Reproducibility and Promote Research Translation
por: Ramirez, F. Daniel, et al.
Publicado: (2017) -
Is preclinical research in cancer biology reproducible enough?
por: Kane, Patrick Bodilly, et al.
Publicado: (2021) -
Correction: The Economics of Reproducibility in Preclinical Research
Publicado: (2018)