N-carbamylglutamate restores nitric oxide synthesis and attenuates high altitude-induced pulmonary hypertension in Holstein heifers ascended to high altitude

BACKGROUND: High-altitude pulmonary hypertension (HAPH) is a life-threating condition for animals in high altitude, and disturbance of endothelial nitric oxide (NO) synthesis contributes to its pathogenesis. N-carbamylglutamate (NCG), which enhances arginine synthesis, promotes endogenous synthesis...

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Detalles Bibliográficos
Autores principales: Wang, Shuxiang, Azarfar, Arash, Wang, Yajing, Cao, Zhijun, Li, Shengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120069/
https://www.ncbi.nlm.nih.gov/pubmed/30186602
http://dx.doi.org/10.1186/s40104-018-0277-6

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