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Importance of Val567 on heme environment and substrate recognition of neuronal nitric oxide synthase

Nitric oxide (NO) produced by mammalian nitric oxide synthases (mNOSs) is an important mediator in a variety of physiological functions. Crystal structures of mNOSs have shown strong conservation of the active‐site residue Val567 (numbering for rat neuronal NOS, nNOS). NOS‐like proteins have been id...

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Detalles Bibliográficos
Autores principales: Olsbu, Inger K., Zoppellaro, Giorgio, Andersson, K. Kristoffer, Boucher, Jean‐Luc, Hersleth, Hans‐Petter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120233/
https://www.ncbi.nlm.nih.gov/pubmed/30186754
http://dx.doi.org/10.1002/2211-5463.12503