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A drug‐repositioning screen for primary pancreatic ductal adenocarcinoma cells identifies 6‐thioguanine as an effective therapeutic agent for TPMT‐low cancer cells
Pancreatic cancer is one of the most difficult cancers to cure due to the lack of early diagnostic tools and effective therapeutic agents. In this study, we aimed to isolate new bioactive compounds that effectively kill pancreatic ductal adenocarcinoma (PDAC) cells, but not untransformed, human panc...
Autores principales: | Kim, Inki, Choi, Yeon‐Sook, Song, Jae Hwi, Choi, Eun A, Park, Sojung, Lee, Eun Ji, Rhee, Je‐Keun, Kim, Song Cheol, Chang, Suhwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120251/ https://www.ncbi.nlm.nih.gov/pubmed/30055072 http://dx.doi.org/10.1002/1878-0261.12364 |
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