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A drug‐repositioning screen for primary pancreatic ductal adenocarcinoma cells identifies 6‐thioguanine as an effective therapeutic agent for TPMT‐low cancer cells

Pancreatic cancer is one of the most difficult cancers to cure due to the lack of early diagnostic tools and effective therapeutic agents. In this study, we aimed to isolate new bioactive compounds that effectively kill pancreatic ductal adenocarcinoma (PDAC) cells, but not untransformed, human panc...

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Detalles Bibliográficos
Autores principales: Kim, Inki, Choi, Yeon‐Sook, Song, Jae Hwi, Choi, Eun A, Park, Sojung, Lee, Eun Ji, Rhee, Je‐Keun, Kim, Song Cheol, Chang, Suhwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120251/
https://www.ncbi.nlm.nih.gov/pubmed/30055072
http://dx.doi.org/10.1002/1878-0261.12364

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